WO2003013239A3 - Verfahren zur devitalisierung natürlicher organe und/oder zur bereitstellung extrazellulärer matrices zum 'tissue-engineering' - Google Patents

Verfahren zur devitalisierung natürlicher organe und/oder zur bereitstellung extrazellulärer matrices zum 'tissue-engineering' Download PDF

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Publication number
WO2003013239A3
WO2003013239A3 PCT/EP2002/008781 EP0208781W WO03013239A3 WO 2003013239 A3 WO2003013239 A3 WO 2003013239A3 EP 0208781 W EP0208781 W EP 0208781W WO 03013239 A3 WO03013239 A3 WO 03013239A3
Authority
WO
WIPO (PCT)
Prior art keywords
organs
devitalisation
preparation
tissue engineering
natural
Prior art date
Application number
PCT/EP2002/008781
Other languages
English (en)
French (fr)
Other versions
WO2003013239A2 (de
Inventor
Peter Lamm
Gerd Juchem
Original Assignee
Peter Lamm
Gerd Juchem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Peter Lamm, Gerd Juchem filed Critical Peter Lamm
Priority to US10/485,947 priority Critical patent/US20050009000A1/en
Priority to AU2002340807A priority patent/AU2002340807A1/en
Priority to EP02774502A priority patent/EP1414295A2/de
Publication of WO2003013239A2 publication Critical patent/WO2003013239A2/de
Publication of WO2003013239A3 publication Critical patent/WO2003013239A3/de

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0236—Mechanical aspects
    • A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
    • A01N1/0247—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components for perfusion, i.e. for circulating fluid through organs, blood vessels or other living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts

Abstract

Die Erfindung betrifft Verfahren zur Devitalisierung und Konservierung menschlicher und Tierischer Organe und Gewebe, bevorzugt jedoch natürlicher Hohlorgane und deren sämtlicher Bestandteile, insbesondere von Blutgefässen und Herzklappen. Des weiteren betrifft die Erfindung Verfahren zur Herstellung von Matrices für den Teil- und Neuaufbau von Organen und Geweben. Darüber hinaus betrifft die Erfindung Organe und Gewebe, insbesondere natürliche und künstliche Hohlorgane, die nach den erfindungsgemässen Verfahren erhältlich sind. Weiterhin betrifft die Erfindung den klinischen Einsatz und die Verwendung der hergestellten Organe und Gewebe in der Medizin und Veterinärmedizin, vorzugsweise in der Herz- und Gefässchirurgie. Weiterhin betrifft die Erfindung neue Kulturmedien.
PCT/EP2002/008781 2001-08-06 2002-08-06 Verfahren zur devitalisierung natürlicher organe und/oder zur bereitstellung extrazellulärer matrices zum 'tissue-engineering' WO2003013239A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US10/485,947 US20050009000A1 (en) 2001-08-06 2002-08-06 Method for the devitalisation of natural organs and/or for the preparation of extracellular matrices for tissue engineering
AU2002340807A AU2002340807A1 (en) 2001-08-06 2002-08-06 Method for the devitalisation of natural organs and/or for the preparation of extracellular matrices for tissue engineering
EP02774502A EP1414295A2 (de) 2001-08-06 2002-08-06 Verfahren zur devitalisierung natürlicher organe und/oder zur bereitstellung extrazellulärer matrices zum "tissue-engineering"

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10138564.1 2001-08-06
DE10138564A DE10138564B4 (de) 2001-08-06 2001-08-06 Verfahren zur Devitalisierung natürlicher Organe und/oder zur Bereitstellung extrazellulärer Matrices zum "Tissue-Engineering"

Publications (2)

Publication Number Publication Date
WO2003013239A2 WO2003013239A2 (de) 2003-02-20
WO2003013239A3 true WO2003013239A3 (de) 2003-10-02

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/008781 WO2003013239A2 (de) 2001-08-06 2002-08-06 Verfahren zur devitalisierung natürlicher organe und/oder zur bereitstellung extrazellulärer matrices zum 'tissue-engineering'

Country Status (5)

Country Link
US (1) US20050009000A1 (de)
EP (1) EP1414295A2 (de)
AU (1) AU2002340807A1 (de)
DE (1) DE10138564B4 (de)
WO (1) WO2003013239A2 (de)

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USRE45130E1 (en) 2000-02-28 2014-09-09 Jenavalve Technology Gmbh Device for fastening and anchoring cardiac valve prostheses
US8834561B2 (en) 2005-10-28 2014-09-16 Jenavalve Technology Gmbh Device for the implantation and fixation of prosthetic valves
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
US9138315B2 (en) 2007-04-13 2015-09-22 Jenavalve Technology Gmbh Medical device for treating a heart valve insufficiency or stenosis
US9168130B2 (en) 2008-02-26 2015-10-27 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US9265631B2 (en) 2008-02-26 2016-02-23 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US9295551B2 (en) 2007-04-13 2016-03-29 Jenavalve Technology Gmbh Methods of implanting an endoprosthesis
US9339386B2 (en) 2007-04-13 2016-05-17 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficency
US9439759B2 (en) 2008-02-26 2016-09-13 Jenavalve Technology, Inc. Endoprosthesis for implantation in the heart of a patient
US9510947B2 (en) 2011-10-21 2016-12-06 Jenavalve Technology, Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient
US9597182B2 (en) 2010-05-20 2017-03-21 Jenavalve Technology Inc. Catheter system for introducing an expandable stent into the body of a patient

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DE10010073B4 (de) * 2000-02-28 2005-12-22 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verankerung für implantierbare Herzklappenprothesen
US7964387B2 (en) * 2000-10-06 2011-06-21 Michael Dancu Method of conditioning a hybrid synthetic tubular structure to yield a functional human hybrid hemodialysis access graft
US7968329B2 (en) * 2000-10-06 2011-06-28 Michael Dancu Method of conditioning a hybrid synthetic tubular structure to yield a functional human hybrid coronary bypass graft
FR2828263B1 (fr) 2001-08-03 2007-05-11 Philipp Bonhoeffer Dispositif d'implantation d'un implant et procede d'implantation du dispositif
DE10326764A1 (de) * 2003-06-13 2004-12-30 Biotest Ag Endothel-protektive Perfusionslösung, eine Apparatur und Verfahren zur Konservierung des Endothels in isolierten Hohlorganen und biologischen Gefäßen
DE102005003632A1 (de) 2005-01-20 2006-08-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Katheter für die transvaskuläre Implantation von Herzklappenprothesen
DE102005052628B4 (de) 2005-11-04 2014-06-05 Jenavalve Technology Inc. Selbstexpandierendes, flexibles Drahtgeflecht mit integrierter Klappenprothese für den transvaskulären Herzklappenersatz und ein System mit einer solchen Vorrichtung und einem Einführkatheter
US20070213813A1 (en) 2005-12-22 2007-09-13 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
CN101801431B (zh) * 2007-06-22 2014-11-19 循环生物制品有限责任公司 流体浓缩器和自体浓缩体液及其使用方法
US8398704B2 (en) 2008-02-26 2013-03-19 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
WO2011104269A1 (en) 2008-02-26 2011-09-01 Jenavalve Technology Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US8468667B2 (en) * 2009-05-15 2013-06-25 Jenavalve Technology, Inc. Device for compressing a stent
WO2011124280A1 (en) * 2010-04-08 2011-10-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Zeodration method for the preservation of blood platelets
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US11278406B2 (en) 2010-05-20 2022-03-22 Jenavalve Technology, Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect
JP2013526388A (ja) 2010-05-25 2013-06-24 イエナバルブ テクノロジー インク 人工心臓弁、及び人工心臓弁とステントを備える経カテーテル搬送体内プロテーゼ
US8834928B1 (en) 2011-05-16 2014-09-16 Musculoskeletal Transplant Foundation Tissue-derived tissugenic implants, and methods of fabricating and using same
US9878127B2 (en) 2012-05-16 2018-01-30 Jenavalve Technology, Inc. Catheter delivery system for heart valve prosthesis
EP3027235A1 (de) 2013-07-30 2016-06-08 Musculoskeletal Transplant Foundation Aus einem azellulären weichgewebe gewonnene matrizen und verfahren zur herstellung davon
CN105491978A (zh) 2013-08-30 2016-04-13 耶拿阀门科技股份有限公司 用于假体瓣膜的径向可折叠框架及其制造方法
US10709555B2 (en) 2015-05-01 2020-07-14 Jenavalve Technology, Inc. Device and method with reduced pacemaker rate in heart valve replacement
US10531957B2 (en) 2015-05-21 2020-01-14 Musculoskeletal Transplant Foundation Modified demineralized cortical bone fibers
WO2017011653A1 (en) * 2015-07-15 2017-01-19 The University Of Florida Research Foundation, Inc. Tissue decellularization methods
US10912864B2 (en) 2015-07-24 2021-02-09 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
CN105638641B (zh) * 2016-03-16 2018-05-29 麦重伟 葡甘露胶在标本保存中的应用及其使用方法
EP3454795B1 (de) 2016-05-13 2023-01-11 JenaValve Technology, Inc. Herzklappenprotheseneinführungssystem zur einführung einer herzklappenprothese mit einführerhülse und ladesystem
CN110392557A (zh) 2017-01-27 2019-10-29 耶拿阀门科技股份有限公司 心脏瓣膜模拟

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Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE45130E1 (en) 2000-02-28 2014-09-09 Jenavalve Technology Gmbh Device for fastening and anchoring cardiac valve prostheses
USRE45790E1 (en) 2005-10-28 2015-11-03 Jenavalve Technology Gmbh Device for the implantation and fixation of prosthetic valves
US8834561B2 (en) 2005-10-28 2014-09-16 Jenavalve Technology Gmbh Device for the implantation and fixation of prosthetic valves
US9402717B2 (en) 2005-10-28 2016-08-02 Jenavalve Technology, Inc. Device for the implantation and fixation of prosthetic valves
USRE45962E1 (en) 2005-10-28 2016-04-05 Jenavalve Technology Gmbh Device for the implantation and fixation of prosthetic valves
US9339386B2 (en) 2007-04-13 2016-05-17 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficency
US9295551B2 (en) 2007-04-13 2016-03-29 Jenavalve Technology Gmbh Methods of implanting an endoprosthesis
US9138315B2 (en) 2007-04-13 2015-09-22 Jenavalve Technology Gmbh Medical device for treating a heart valve insufficiency or stenosis
US9445896B2 (en) 2007-04-13 2016-09-20 Jenavalve Technology, Inc. Methods for treating a heart valve insufficiency or stenosis
US9265631B2 (en) 2008-02-26 2016-02-23 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US9168130B2 (en) 2008-02-26 2015-10-27 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
US9439759B2 (en) 2008-02-26 2016-09-13 Jenavalve Technology, Inc. Endoprosthesis for implantation in the heart of a patient
US9597182B2 (en) 2010-05-20 2017-03-21 Jenavalve Technology Inc. Catheter system for introducing an expandable stent into the body of a patient
US9510947B2 (en) 2011-10-21 2016-12-06 Jenavalve Technology, Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient

Also Published As

Publication number Publication date
US20050009000A1 (en) 2005-01-13
DE10138564A1 (de) 2003-02-27
DE10138564B4 (de) 2007-07-12
AU2002340807A1 (en) 2003-02-24
EP1414295A2 (de) 2004-05-06
WO2003013239A2 (de) 2003-02-20

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